{"id":106,"date":"2012-11-05T11:32:45","date_gmt":"2012-11-05T15:32:45","guid":{"rendered":"https:\/\/sites.owu.edu\/wolverton\/?page_id=106"},"modified":"2016-12-01T08:50:42","modified_gmt":"2016-12-01T13:50:42","slug":"nucleic-acids","status":"publish","type":"page","link":"https:\/\/sites.owu.edu\/wolverton\/teaching\/cell-bio\/nucleic-acids\/","title":{"rendered":"Nucleic Acids"},"content":{"rendered":"<p><!--:en--><\/p>\n<h2 id=\"links\">Links<\/h2>\n<p><a href=\"http:\/\/www.nature.com\/principles\/ebooks\/introduction-to-cell-biology-4570805\/4569761\">Principles Module 12<\/a><\/p>\n<h2 id=\"objectives\">Objectives<\/h2>\n<ul>\n<li>Describe the general structure of nucleic acids<\/li>\n<li>Discuss how nucleic acids encode information<\/li>\n<\/ul>\n<h2 id=\"keypoints\">Key points<\/h2>\n<ul>\n<li>nucleic acid polymers are not repeats of the identical monomer<\/li>\n<li>nucleotides are made up of a sugar, a nitrogenous base, and a phosphate\n<ul>\n<li>five kinds based on differing N-base<\/li>\n<li>purines (A, G) and pyrimidines (C, T, U)<\/li>\n<\/ul>\n<\/li>\n<li>phosphodiester bond formation is energy-releasing<\/li>\n<li>DNA secondary structure forms double-helix\n<ul>\n<li>antiparallel strands<\/li>\n<li>bases toward inside, pair by H-bonding<\/li>\n<\/ul>\n<\/li>\n<li>each strand acts as a template for new strand by base-pairing<\/li>\n<li>sequences of DNA encode genes, which specify proteins<\/li>\n<\/ul>\n<h2 id=\"in-classactivities\">In-class activities<\/h2>\n<ul>\n<li>discuss <a href=\"http:\/\/www.nature.com\/principles\/content\/ne0000\/ne0000\/ne0000\/ne0000\/171506\/PLS_Gen12_watsoncrick.zip\">classic paper bundle<\/a><\/li>\n<\/ul>\n<p><!--:--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Links Principles Module 12 Objectives Describe the general structure of nucleic acids Discuss how nucleic acids encode information Key points nucleic acid polymers are not repeats of the identical monomer nucleotides are made up of a sugar, a nitrogenous base, and a phosphate five kinds based on differing N-base purines (A, G) and pyrimidines (C, [&hellip;]<\/p>\n","protected":false},"author":40,"featured_media":0,"parent":447,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-106","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages\/106","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/users\/40"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/comments?post=106"}],"version-history":[{"count":1,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages\/106\/revisions"}],"predecessor-version":[{"id":511,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages\/106\/revisions\/511"}],"up":[{"embeddable":true,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages\/447"}],"wp:attachment":[{"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/media?parent=106"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}