{"id":103,"date":"2012-11-05T11:32:21","date_gmt":"2012-11-05T15:32:21","guid":{"rendered":"https:\/\/sites.owu.edu\/wolverton\/?page_id=103"},"modified":"2016-12-01T08:50:41","modified_gmt":"2016-12-01T13:50:41","slug":"enzymes","status":"publish","type":"page","link":"https:\/\/sites.owu.edu\/wolverton\/teaching\/cell-bio\/enzymes\/","title":{"rendered":"Enzymes"},"content":{"rendered":"<p><!--:en--><\/p>\n<h2 id=\"links\">Links<\/h2>\n<p><a href=\"http:\/\/www.nature.com\/principles\/ebooks\/introduction-to-cell-biology-4570805\/4569777\">Principles Module 11<\/a><\/p>\n<h2 id=\"objectives\">Objectives<\/h2>\n<ul>\n<li>Describe what an enzyme is and what it does<\/li>\n<li>Discuss the ways enzymes are regulated<\/li>\n<li>Explain the kinds of enzyme inhibition and example scenarios<\/li>\n<\/ul>\n<h2 id=\"keypoints\">Key points<\/h2>\n<ul>\n<li>enzymes speed up reactions that would happen anyway<\/li>\n<li>terminology: substrate, product, naming, active site<\/li>\n<li>enzymes lower the activation energy of a reaction by making more stable transition states\n<ul>\n<li>bring substrates together in correct orientation<\/li>\n<li>placing bond-angle stress on reactive group<\/li>\n<li>facilitating oxidation or reduction of substrate<\/li>\n<\/ul>\n<\/li>\n<li>enzymes are not permanently changed by reactions, cycle and reused<\/li>\n<li>very highly specific for substrates<\/li>\n<li>regulation of enzymes by feedback inhibition\n<ul>\n<li>competitive inhibitors bind to active site<\/li>\n<li>allosteric inhibitors bind to other site and change active site<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"in-classactivities\">In-class activities<\/h2>\n<p>Read the article <a href=\"http:\/\/www.sciencedaily.com\/releases\/2009\/03\/090323212023.htm\"><em>New Enzymes Created For Biofuel Production<\/em><\/a> and respond to the following questions:<\/p>\n<ul>\n<li>What reaction did the newly-invented enzymes catalyze? Be specific and use chemical terms and structures.<\/li>\n<li>What are some sources of cellulose, and why is it preferrable to starch as a starting material for biofuel?<\/li>\n<li>How did the researchers \u2018create\u2019 these new enzymes?<\/li>\n<li>In what ways do you think the new enzymes differ from the natural ones?<\/li>\n<li>Name some of the properties of the new enzymes compared to the natural ones.<\/li>\n<\/ul>\n<p><!--:--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Links Principles Module 11 Objectives Describe what an enzyme is and what it does Discuss the ways enzymes are regulated Explain the kinds of enzyme inhibition and example scenarios Key points enzymes speed up reactions that would happen anyway terminology: substrate, product, naming, active site enzymes lower the activation energy of a reaction by making [&hellip;]<\/p>\n","protected":false},"author":40,"featured_media":0,"parent":447,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-103","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages\/103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/users\/40"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/comments?post=103"}],"version-history":[{"count":1,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages\/103\/revisions"}],"predecessor-version":[{"id":501,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages\/103\/revisions\/501"}],"up":[{"embeddable":true,"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/pages\/447"}],"wp:attachment":[{"href":"https:\/\/sites.owu.edu\/wolverton\/wp-json\/wp\/v2\/media?parent=103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}